Anti-ATF1 Rabbit Monoclonal Antibody(BM4696-100ul)

Anti-ATF1 Rabbit Monoclonal An

tibody(BM4696-100ul)
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  • ¥1960
  • BOSTER已认证
  • BM4696-100ul
  • 中国
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 BM4696
    产品名称 Anti-ATF1 Antibody
    基因名 ATF1
    抗体来源 Rabbit
    克隆 Monoclonal
    抗体亚型 Rabbit
    分子量 38KD
    免疫原 A synthesized peptide derived from human ATF1
    内容 500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    纯化方式 Affinity-chromatography
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.
    研究类别 1. ucman, J., Delattre, O., Desmaze, C., Epstein, A. L., Stenman, G., Speleman, F., Fletchers, C. D. M., Aurias, A., Thomas, G. EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nature Genet. 4: 341-345, 1993.2. "Entrez Gene: ATF1 activating transcription factor 1"
    Uniprot ID ATF1: P18846

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    [list_product_images]Western blot analysis of ATF1 expression in Hela cell lysate.[/list_product_images]

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