Anti-Phospho-Synapsin I (S9) Rabbit Monoclonal Antibody(BM4501-100ul)

Anti-Phospho-Synapsin I (S9) R

abbit Monoclonal Antibody(BM4501-100ul)
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  • ¥1960
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  • BM4501-100ul
  • 中国
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 BM4501
    产品名称 Anti-Phospho SYN1 (S9) Antibody
    基因名 SYN1
    抗体来源 Rabbit
    克隆 Monoclonal
    抗体亚型 Rabbit
    分子量 78KD
    免疫原 A synthesized peptide derived from human Phospho-Synapsin I (S9)
    内容 500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    纯化方式 Affinity-chromatography
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene. This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
    研究类别 1. "Entrez Gene: SYN1 synapsin I".2. Huttner WB, Schiebler W, Greengard P, De Camilli P (May 1983). "Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation". J. Cell Biol. 96 (5): 1374–88.3. Südhof TC (May 1990). "The structure of the human synapsin I gene and protein". J. Biol. Chem. 265 (14): 7849–52.
    Uniprot ID SYN1: P17600

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    [list_product_images]Western blot analysis of Phospho-Synapsin I (S9) expression in (1) Human brain lysate; (2) Human brain lysate treated with AP.[/list_product_images]

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