Anti-EPHB2 Antibody(BA2031-1-100ul)

Anti-EPHB2 Antibody(BA2031-1-1

00ul)
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  • ¥1960
  • BOSTER已认证
  • BA2031-1-100ul
  • 中国
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 BA2031-1
    产品名称 Anti-EPHB3 Antibody
    基因名 EPHB3
    抗体来源 Rabbit
    克隆 Polyclonal
    抗体亚型 Rabbit IgG
    免疫原 A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor B3(982-998aa SIQDMRLQMNQTLPVQV), identical to the related rat and mouse sequences.
    内容 500 ug/ml antibody with PBS ,0.02% NaN3 , 1 mg BSA and 50% glycerol.
    纯化方式 Immunogen affinity purified.
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 Ephrin Receptor EphB3, is also known as human embryo kinase2(HEK2) or Eph-like tyrosine kinase2(ETK2). HEK2, which is a member of the EPH/ELK family of tyrosine kinases, encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and 2 fibronectin repeats. The EPHB3 gene is mapped to human chromosome 3q21-qter. HEK2 interacts with 2 ligands of EPH-related kinases(LERKs), namely, LERK2(EFNB1) and LERK5(EFNB2). Coincubation of HEK2- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of HEK2 and LERK2 results in reduced kinase activity of HEK2.
    研究类别 1. Bohme, B., Holtrich, U., Wolf, G., Luzius, H., Grzeschik, K.-H., Strebhardt, K., Rubsamen-Waigmann, H.PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2.Oncogene 8: 2857-2862, 1993. 2. Bohme, B., VandenBos, T., Cerretti, D. P., Park, L. S., Holtrich, U., Rubsamen-Waigmann, H., Strebhardt, K.Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity.J. Biol. Chem. 271: 24747-24752, 1996.
    Uniprot ID EPHB3: P54753
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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    [list_product_images]EPHB2(BA2031-1)肺癌标本, 石蜡切片, SABC法, DAB显色.[/list_product_images]

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