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Anti-CNPase Antibody(A01017-10

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  • ¥1960
  • BOSTER已认证
  • A01017-100ul
  • 中国
  • 2025年07月08日
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    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 A01017
    产品名称 Anti-CNP Antibody
    基因名 CNP
    抗体来源 Rabbit
    克隆 Polyclonal
    抗体亚型 Rabbit IgG
    分子量 48KD
    免疫原 A synthetic peptide corresponding to a sequence in the middle region of human CNPase (142-178aa QYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
    内容 500 ug/ml antibody with PBS ,0.02% NaN3 , 1 mg BSA and 50% glycerol.
    纯化方式 Immunogen affinity purified.
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 2',3'-Cyclic-nucleotide 3'-phosphodiesterase, also known as CNPase, is an enzyme that in humans is encoded by the CNP gene. And this gene is mapped to 17q21.2. CNPase is named for its ability to catalyze the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. CNPase is thought to play a critical role in the events leading up to myelination. Additionally, CNPase has been demonstrated to inhibit the replication of HIV-1 and other primate lentiviruses by binding the retroviral Gag protein and inhibiting the genesis of nascent viral particles.
    研究类别 1. "Entrez Gene: CNP 2',3'-cyclic nucleotide 3' phosphodiesterase".2. Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR (Jan 2008). "Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts". Glia. 56 (1): 118–33.3. Sprinkle TJ, Lanclos KD, Lapp DF (Jul 1992). "Assignment of the human 2',3'-cyclic nucleotide 3'-phosphohydrolase gene to chromosome 17".Genomics. 13 (3): 877–80.
    Uniprot ID CNP: P09543
    推荐配套的二抗和检测试剂 Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。

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    [list_product_images]Figure 1. Western blot analysis of CNPase using anti-CNPase antibody (A01017). lane 1: rat brain tissue lysates,lane 2: mouse brain tissue lysates,lane 3: HELA whole cell lysates. anti-CNPase antigen affinity purified polyclonal antibody (Catalog # A01017)probed with a goat anti-rabbit IgG-HRP secondary antibody The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) . A specific band was detected for CNPase at approximately 47KD. The expected band size for CNPase is at 47KD.[/list_product_images]

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