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50ul
货号 | A09297 |
---|---|
产品名称 | Anti-PTPIP51/RMDN3 Antibody |
基因名 | RMDN3 |
抗体来源 | Rabbit |
抗体亚型 | Rabbit IgG |
分子量 | 55KD |
免疫原 | E.coli-derived human PTPIP51/RMDN3 recombinant protein (Position: Q45-R438). |
内容 | 500 ug/ml antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500 ug/ml |
产品形态 | Liquid |
保存条件 | 12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
背景资料 | Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15. Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle. |
研究类别 | 1. De Vos, K. J., Morotz, G. M., Stoica, R., Tudor, E. L., Lau, K.-F., Ackerly, S., Warley, A., Shaw, C. E., Miller, C. C. J. VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Hum. Molec. Genet. 21: 1299-1311, 2012. 2. Lv, B. F., Yu, C. F., Chen, Y. Y., Lu, Y., Guo, J. H., Song, Q. S., Ma, D. L., Shi, T. P., Wang, L. Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosis. Apoptosis 11: 1489-1501, 2006. 3. Oishi, K., Okano, H., Sawa H. RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans. J. Cell Biol. 179: 1149-1162, 2007. Note: Erratum: J. Cell Biol. 186: 629 only, 2009. |
Uniprot ID | RMDN3: Q96TC7 |
推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC. |
为了提供优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot (WB): | 1:500-2000 |
Immunohistochemistry in paraffin section (IHC): | 1:50-400 |
Immunofluorescence (IF): | 1:50-400 |
Immunocytochemistry/Immunofluorescence (ICC/IF): | 1:50-400 |
Flow cytometry (FCM): | 1-3 μg/1x106 cells |
ELISA: | 1:100-1000 |
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
*稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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