背景资料 |
Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. |
研究类别 |
1. Arad, M., Maron, B. J., Gorham, J. M., Johnson, W. H., Jr., Saul, J. P., Perez-Atayde, A. R., Spirito, P., Wright, G. B., Kanter, R. J., Seidman, C. E., Seidman, J. G. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. New Eng. J. Med. 352: 362-372, 2005. 2. Bird, A. P. HTF islands as gene markers in the vertebrate nucleus. Trends Genet. 3: 342-347, 1987.3. Blair, H. J., Ho, M., Monaco, A. P., Fisher, S., Craig, I. W., Boyd, Y. High-resolution comparative mapping of the proximal region of the mouse X chromosome. Genomics 28: 305-310, 1995. |