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- 详细信息
- 技术资料
- 库存:
大量
- 供应商:
广州威佳科技有限公司
- 规格:
50ul
产品概况
| 货号 | M02799-1 |
|---|---|
| 产品名称 | Anti-CoREST/RCOR1 Antibody |
| 基因名 | RCOR1 |
| 抗体来源 | Rabbit |
| 克隆 | Monoclonal(Clone:18R91) |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 66KD |
| 免疫原 | A synthesized peptide derived from human CoREST |
| 内容 | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.5mg/ml BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene. This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). |
| 研究类别 | 1. Andres, M. E., Burger, C., Peral-Rubio, M. J., Battaglioli, E., Anderson, M. E., Grimes, J., Dallman, J., Ballas, N., Mandel, G. CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc. Nat. Acad. Sci. 96: 9873-9878, 1999. 2. Gocke, C. B., Yu, H. ZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. PLoS One 3: E3255, 2008. Note: Electronic Article.3. Lee, M. G., Wynder, C., Cooch, N., Shiekhattar, R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437: 432-435, 2005. |
| Uniprot ID | RCOR1: Q9UKL0 |
产品应用细节
为了提供优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:1000-5000 |
| IHC: | 1:50-1:200 |
| ICC/IF: | 1:50-1:200 |
*稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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[list_product_images]Western blot analysis of CoREST expression in Molt-4 cell lysate.[/list_product_images]
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Anti-CoREST/RCOR1 Antibody(M02799-1-50ul)
¥1180







