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- BOSTER
- A12703-1-50ul
- 中国
- 2025年07月05日
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- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
50ul
产品概况
| 货号 | A12703-1 |
|---|---|
| 产品名称 | Anti-FOXRED2 Antibody |
| 基因名 | FOXRED2 |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 80KD |
| 免疫原 | E.coli-derived human FOXRED2 recombinant protein (Position: Q44-Q623). |
| 内容 | 500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D. |
| 研究类别 | 1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/25/2011.2. Riemer, J., Appenzeller-Herzog, C., Johansson, L., Bodenmiller, B., Hartmann-Petersen, R., Ellgaard, L. A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proc. Nat. Acad. Sci. 106: 14831-14836, 2009. |
| Uniprot ID | FOXRED2: Q8IWF2 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
| ELISA: | 1:100-1000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Figure 1. Western blot analysis of anti- FOXRED2 Antibody (A12703-1). The sample well of each lane was loaded with 50ug of sample under reducing conditions.
Lane 1: Hela whole cell lysates,
Lane 2: HepG2 whole cell lysates,
Lane 3: Jurkat whole cell lysates,
Lane 4: C6 whole cell lysates,
Lane 5: NIH/3T3 whole cell lysates.
Use rabbit anti- FOXRED2 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for FOXRED2 at approximately 80KD. The expected band size for FOXRED2 is at 78KD.[/list_product_images]
Lane 1: Hela whole cell lysates,
Lane 2: HepG2 whole cell lysates,
Lane 3: Jurkat whole cell lysates,
Lane 4: C6 whole cell lysates,
Lane 5: NIH/3T3 whole cell lysates.
Use rabbit anti- FOXRED2 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for FOXRED2 at approximately 80KD. The expected band size for FOXRED2 is at 78KD.[/list_product_images]
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Anti-FOXRED2 Antibody(A12703-1-50ul)
￥1180
