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- BOSTER
- PB9903-50ul
- 中国
- 2025年07月11日
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- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
50ul
产品概况
| 货号 | PB9903 |
|---|---|
| 产品名称 | Anti-TRPM5 Antibody |
| 基因名 | TRPM5 |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 131KD |
| 免疫原 | E.coli-derived human TRPM5 recombinant protein (Position: S1021-Q1108). Human TRPM5 shares 87.5% amino acid (aa) sequence identity with mouse TRPM5. |
| 内容 | 500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a protein that in humans is encoded by the TRPM5 gene. This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. |
| 研究类别 | 1. Emily R Liman (2010). "Changing Taste by Targeting the Ion Channel TRPM5".The Open Drug Discovery Journal 2: 98–102.2. Liman ER (2007). "TRPM5 and taste transduction". Handb Exp Pharmacol. Handbook of Experimental Pharmacology 179 (179): 287–98. |
| Uniprot ID | TRPM5: Q9NZQ8 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。 |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
| Immunohistochemistry(Paraffin-embedded Section): | 1:50-400 |
| (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. | |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Western blot analysis of TRPM5 expression in SMMC whole cell lysates (lane 1) and 293T whole cell lysates (lane 2). TRPM5 at 131KD was detected using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody (Catalog # PB9903) at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).|TRPM5 was detected in paraffin-embedded sections of mouse brain tissues using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody (Catalog # PB9903) at 1 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).|TRPM5 was detected in paraffin-embedded sections of rat testis tissues using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody (Catalog # PB9903) at 1 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).|TRPM5 was detected in paraffin-embedded sections of human prostatic cancer tissues using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody (Catalog # PB9903) at 1 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).[/list_product_images]
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Anti-TRPM5 Antibody(原货号PB0949)(PB9903-50ul)
￥1180
