Anti-Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Monoclonal Antibody(BM5435-50ul)

Anti-Phospho-PAK4 + PAK5 + PAK

6 (S474 + S560 + S602) Monoclonal Antibody(BM5435-50ul)
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  • ¥1180
  • BOSTER已认证
  • BM5435-50ul
  • 中国
  • 2025年07月11日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      50ul

    产品概况

    货号 BM5435
    产品名称 Anti-Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Antibody
    基因名 PAK4,PAK5,PAK6
    抗体来源 Rabbit
    克隆 Monoclonal
    抗体亚型 Rabbit
    分子量 64,80,75KD
    免疫原 A synthesized peptide derived from human Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival.
    内容 500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    纯化方式 Affinity-chromatography
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
    背景资料 PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Uniprot ID PAK4,PAK5,PAK6: O96013(PAK4-Antigen),Q9P286(PAK5),Q9NQU5(PAK6)

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    [list_product_images]Western blot analysis of Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) expression in U87-MG cell lysate.[/list_product_images]

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