500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
纯化方式
Affinity-chromatography
浓度
500 ug/ml
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
Vinculin is a cytoskeletal protein associated with the cytoplasmic face of both cell-cell and cell-extracellular matrix adherens-type junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Both human and chicken embryo sequences of vinculin contain 1,066 amino acids and, furthermore, that the 2 proteins exhibit a high level of sequence identity(greater than 95%). Vinculinis mapped to 10q22.1-q23.
研究类别
1. Weller, P. A.; Ogryzko, E. P.; Corben, E. B.; Zhidkova, N. I.; Patel, B.; Price, G. J.; Spurr, N. K.; Koteliansky, V. E.; Critchley, D. R. : Complete sequence of human vinculin and assignment of the gene to chromosome 10. Proc. Nat. Acad. Sci. 87: 5667-5671, 1990. 2. Mulligan, L. M.; Gardner, E.; Telenius, H.; Ponder, B. A. J. : Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q. Genomics 13: 1347-1349, 1992.