- ￥1180
- BOSTER
- BM1578-50ul
- 中国
- 2025年07月11日
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- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
50ul
产品概况
| 货号 | BM1578 |
|---|---|
| 产品名称 | Anti-CTSL Antibody |
| 基因名 | CTSL1 |
| 抗体来源 | Mouse |
| 克隆 | Monoclonal(Clone:33/2) |
| 抗体亚型 | Mouse IgG1 |
| 分子量 | 38KD |
| 免疫原 | Procathepsin L isolated from the human lung cancer cell line EPLC 32M1. |
| 内容 | 200ug/ml antibody with PBS ，0.02% NaN3 , 1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization. |
| 研究类别 | 1. Fan, Y.-S.; Byers, M. G.; Eddy, R. L.; Joseph, L.; Sukhatme, V.; Chan, S.-J.; Shows, T. B. : Cathepsin L (CTSL) is located in the chromosome 9q21-q22 region: a related sequence is located on chromosome 10. (Abstract) Cytogenet. Cell Genet. 51: 996 only, 1989. 2. Urbich, C.; Heeschen, C.; Aicher, A.; Sasaki, K.; Bruhl, T.; Farhadi, M. R.; Vajkoczy, P.; Hofmann, W. K.; Peters, C.; Pennacchio, L. A.; Abolmaali, N. D.; Chavakis, E.; Reinheckel, T.; Zeiher, A. M.; Dimmeler, S. : Cathepsin L is required for endothelial progenitor cell-induced neovascularization. Nature Med. 11: 206-213, 2005. |
| Uniprot ID | CTSL1: P07711 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
| Immunohistochemistry in frozen section (IHC-F): | 1:50-400 |
| (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. | |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Figure 1. CTSL1(BM1578)(MW:38KD)HepG2细胞裂解，免疫印迹分析. |Figure 2. CTSL1(BM1578)小鼠肾标本，石蜡切片，SABC法，DAB显色. |Figure 3. CTSL1(BM1578)肠癌标本，石蜡切片，SABC法，DAB显色. |Figure 4. CTSL1(BM1578)肺癌标本，石蜡切片，SABC法，DAB显色.[/list_product_images]
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Anti-Cathepsin L Antibody (monoclonal, 33/2)(BM1578-50ul)
￥1180
