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- BOSTER
- BA3165-2-50ul
- 中国
- 2025年07月10日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
50ul
产品概况
| 货号 | BA3165-2 |
|---|---|
| 产品名称 | Anti-AQP7 Antibody |
| 基因名 | AQP7 |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 37KD |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Aquaporin 7(23-42aa AKIQEILQRKMVREFLAEFM). |
| 内容 | 500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene. The human AQP7 gene is composed of six exons distributing over 6.5 kb. The exon-intron boundaries are identical to those of the human AQP3 gene. The intron sizes are also similar. Moreover, chromosomal localization of AQP7 was assigned to 9p13 by fluorescent in situ hybridization, where AQP3 is also localized, suggesting that 9p13 may be another site of an aquaporin cluster. AQP7 acts as a glycerol facilitator in cardiomyocytes and that glycerol is a substrate for cardiac energy production. AQP7 is down-regulated in women with severe obesity. The expression of this glycerol channel is not affected by type 2 diabetes. |
| 研究类别 | 1. Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem272 (33): 20782–6. 2. "Entrez Gene: AQP7 aquaporin 7"3. Ishibashi, K., Yamauchi, K., Kageyama, Y., Saito-Ohara, F., Ikeuchi, T., Marumo, F., Sasaki, S. Molecular characterization of human aquaporin-7 gene and its chromosomal mapping. Biochim. Biophys. Acta 1399: 62-66, 1998. 4. Hibuse, T., Maeda, N., Nakatsuji, H., Tochino, Y., Fujita, K., Kihara, S., Funahashi, T., Shimomura, I. The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator. Cardiovasc. Res. 83: 34-41, 2009. 5. Ceperuelo-Mallafre, V., Miranda, M., Chacon, M. R., Vilarrasa, N., Megia, A., Gutierrez, C., Fernandez-Real, J. M., Gomez, J. M., Caubet, E., Fruhbeck, G., Vendrell, J. Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in severe obesity but not in type 2 diabetes. J. Clin. Endocr. Metab. 92: 3640-3645, 2007. |
| Uniprot ID | AQP7: O14520 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。 |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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[list_product_images]AQP7(BA3165-2)(MW:37KD)SGC, SMMC, A549, COLO320细胞裂解, 免疫印迹分析.[/list_product_images]
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Anti-AQP7(Aquaporin 7) Antibody(BA3165-2-50ul)
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