Anti-MAP2K2 (phospho Thr394) Polyclonal Antibody

Anti-MAP2K2 (phospho Thr394) P

olyclonal Antibody
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  • ¥1800
  • Solarbio已认证
  • 北京
  • K009408P
  • 2025年07月14日
  • WB IHC-P IP ELISA
  • Rabbit
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human MAP2K2 (phospho Thr394)

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at 2-8°C and light-free

    • 克隆性

      Polyclonal Antibody

    • 目录编号

      K009408P

    • 库存

      咨询客服

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB IHC-P IP ELISA

    • 靶点

      MAP2K2 (phospho Thr394)

    • 抗体英文名

      MAP2K2;MEK2;MKK2;PRKMK2;Dual specificity mitogen-activated protein kinase kinase 2;MAP kinase kinase 2;MAPKK 2;ERK activator kinase 2;MAPK/ERK kinase 2;MEK-2

    • 抗体名

      0

    • 规格

      50ul

    The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

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