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E3 Ligase Ligand-linker Conjugate 101
MCE 国际站:E3 Ligase Ligand-linker Conjugate 101
产品活性:E3 Ligase Ligand-linker Conjugate 101 是 E3 连接酶配体与连接子的缀合物 (E3 Ligase Ligand-Linker Conjugates),由 (S,R,S)-AHPC (HY-125845) 和对应 Linker 构成。(S,R,S)-AHPC 是基于 VH032 的 von Hippel-Lindau (VHL) 配体,可募集 VHL 蛋白。E3 Ligase Ligand-linker Conjugate 101 可作为关键中间体进行完整 PROTACs 分子合成。
研究领域:PROTAC
作用靶点:Ligands for E3 Ligase | E3 Ligase Ligand-Linker Conjugates
相关产品:Lenalidomide | Pomalidomide | CC-885 | Eragidomide | Iberdomide | Thalidomide | VH-298 | VH032 | Cemsidomide | (S,R,S)-AHPC-Me hydrochloride | VH285-PEG4-C4-Cl | ALV2 | Golcadomide | (S,R,S)-AHPC monohydrochloride | VH032-cyclopropane-F | (S,S,S)-AHPC hydrochloride | Thalidomide 4-fluoride | Thalidomide-5-OH | Lenalidomide-Br | (S,R,S)-AHPC-PEG2-N3 | (S,R,S)-AHPC-PEG5-COOH | ALV1 | BC-1215 | ZXH-1-161 | VH032-PEG5-C6-Cl | (S,R,S)-AHPC-PEG3-N3 | (S,R,S)-AHPC-PEG4-N3
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验by fluorescent image analysis. Herein, we demonstrated that the method allows analysis of the intracellular protein stability as regulated by protein-degradation signals or an exogenously expressed E3 ubiquitin ligase.
Studies of the Ubiquitin Proteasome System
modification; NEDD8; E1; E2; E3
【精华】vol 687 Chapter 3 采用Splinkerette-PCR技术对前病毒基因组插入位点进行分离
of methods used to uncover insertion sites have previouslybeen described, including genomic DNA library screening(15), ligation-mediated PCR (6), inverse PCR (16), VISAtechnique (17), T-linker PCR (18), and single nucleotidepolymorphism-based mapping (19
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