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文献和实验cell receptor (TCR) repertoires (1 ,2 ). Thus, TCRαV and TCRβV repertoires have been studied for characterizing of T cells that may play major role in peripheral blood or pathological lesions of patients with autoimmune diseases (3 –6 ).
Retroviral Transfer of T-Cell Receptor Genes into Human Peripheral Blood Lymphocytes
, we have succeeded in redirecting the specificity of peripheral blood T-cells and T-lymphocyte clones by the transfer of T-cell-receptor (TCR) genes from antigen specific T-cell clones into these lymphocytes. The TAA MART-1 is expressed by the majority of human
by the human glucocorticoid receptor α (hGRα), a ligand-dependent transcription factor ubiquitously expressed in almost all tissues and cells. The molecular mechanisms of hGRα action involve (a) binding to glucocorticoids, (b) cytoplasmic to nuclear
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