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文献和实验Isolation of Recombinant DNA Elongation Proteins
This chapter summarizes isolation procedures of four recombinant human proteins crucial for DNA replication: (a) the replicative DNA polymerase (pol) δ, (b) proliferating cell nuclear antigen (PCNA), (c) replication protein A (RP-A), and (d
like PKB. Proapoptotic proteins which can be phosphorylated and inhibited by PKB include BAD (BCL2 Antagonist of Cell Death), human Caspase9, and the forkhead family of transcription factors. PKB can also cause stimulation of NF-KappaB (Nuclear Factor-Kappa
-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD. (2005) Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediatedgene transcription and cell survivalin pancreatic cancer cells. Cancer Res. 65 , 2076–2081. 26. Zakaria S
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