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文献和实验1 月内连登 4 顶刊,这个炙手可热的明星蛋白 GDF15 到底什么来路?
作用。图片来源:Cell Metabolism这是 GDF15 继 2019 年 12 月先后登上 Nature Metabolism 和 Nature 之后,再次出现在顶级期刊上。下面就随着小编来看看 GDF15 这个热门蛋白的来路以及相关的 4 篇论文吧。GDF15 有啥来路?生长分化因子-15(Growth/differentiation factor 15,GDF15)是转化生长因子-β 超家族(TGFβ super family)的一员。此前 GDF15 被发现在创伤过后的多种器官出现明显
with fetal calf serum (FCS). However, serum contains a wide variety of biologically active compounds that might adversely affect hESC growth and differentiation. Thus, cultivation of stem cells in FCS complicates experimental approaches to define
Human Embryonic Stem Cells: Isolation, Maintenance, and Differentiation
diverse lineages are developing. Furthermore, strategies using specific growth factor combinations, cell-cell and cell-extracellular matrix induction systems are being explored for directed differentiation along a desired lineage. However, there is a great
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