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文献和实验The classical complement pathway (CCP) activation is a multimolecular complex, composed of three subcomponents namely C1q, C1r, and C1s. C1q is the recognition subunit of this complex and its binding to the specific targets leads
Detection of Complement Receptors 1 and 2 on Mouse Splenic B Cells Using Flow Cytometry
for the complement component 3 (C3) cleavage fragments C3d(g) and iC3b. Additionally, CR1 is a receptor for C3b and regulates complement convertase activity. CR1 and CR2 have various functions including antigen retention by FDC, regulation of surface complement
Human Complement Components C4A and C4B Genetic Diversities: Complex Genotypes and Phenotypes
. 2000. Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP‐C4‐CYP21‐TNX (RCCX) modules in Caucasians: The load of RCCX genetic diversity on MHC‐associated disease. J. Exp. Med. 191:2183‐2196
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