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文献和实验Assays of Glucose Entry, Glucose Transporter Amount, and Translocation
and other hormones (1 ,2 ). Indeed, in those tissues, glucose transporter 4 (GLUT4) is the chief isoform which is, in basal conditions, retained in a specific intracellular storage compartment (3 ). The GLUT4-containing vesicles are translocated to the plasma
Study of Glucose Uptake in Adipose Cells
. One notable exception is the glucose transporter isoform 4 (Glut4), which is specifically expressed in insulin sensitive tissues, i.e., skeletal muscle, heart muscle, and fat, and is responsible for the insulin effect on blood glucose clearance
The Measurement of GLUT4 Translocation in 3T3-L1 Adipocytes
uptake into muscle and fat is the translocation of glucose transporter 4 (GLUT4) to the cell surface from intracellular storage vesicles within the cell. A major advantage in focussing on insulin regulation of glucose transport is that this represents
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