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文献和实验Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
The insulin-like growth factor-binding proteins (IGFBPs) are carrier proteins that are present in all extracellular fluids (1 ). Similarly, insulin-like growth factor-I (IGF-I) and -II are synthesized by connective tissue cells
Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
-2), two types of cell membrane receptors (IGF-1R and IGF-2R), and six binding proteins (IGFBP1-6) (1 ,2 ). This family of growth factors has several important functions. IGF-mediated activation of the IGF-1 receptor stimulates the signal transduction pathway
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