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Biotinylated Anti-Human IL-36γ (IL-1F9) (1mg)
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named
IL-36α (IL-1F6), β (IL- 1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and
in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor,
which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor
with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an
agonist of NF-κB, and can stimulate the inflammatory response in bronchial epithelial cells.
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Biotinylated Anti-Human IL-36γ (IL-1F9) (1mg)
¥56550








