- ￥33738
- PeproTech
- 400-04-1MG
- 2025年07月11日
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1mg
Rat IL-4 (1mg)
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell
proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow
stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells,
characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-
10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is
the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4
production by Th2 cells has been associated with elevated IgE production and allergy
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Rat IL-4 (1mg)
￥33738
