- ￥705
- PeproTech
- 315-03
- 美国
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 供应商：
PeproTech(派普泰克)
- 英文名：
Recombinant Murine GM-CSF
- 规格：
5ug
Murine GM-CSF (5ug)www.peprotech.com/zh/recombinant-murine-gm-csf
Synonyms：Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Description : GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 124 amino acids residues
Catalog #:315-03
Source :E.coli
Purity :Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level :Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity :The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Selected References :Selected List of References Citing This Product
AA Sequence :MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
PubMed Link :GM-CSF+AND+mouse
Country of Origin :USA
Special Sizes:Many products can be ordered in custom sizes. Please click here to contact with your request.
Usage:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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文献和实验Murine Bone Marrow-Derived Macrophages
macrophage colony stimulating factor (GM-CSF), or interleukin-3 (IL-3), they represent an important primary cell source for studies of the actions and interactions of these three growth factors. The principles underlying the method are: (1) to generate
Generation and Characterization of Murine Alternatively Activated Macrophages
can also be skewed during differentiation in vitro, and the resultant phenotype depends upon the cytokine provided to support their differentiation. In murine macrophages, MCSF promotes differentiation to an M1 phenotype, GM-CSF promotes differentiation to an M2
Generation of Langerhans Cell-Like Dendritic Cells from Murine Fetal Skin
and lymphoid organ DC was provided by Schuler et al. several years ago when they demonstrated that epidermal LC cultured in GM-CSF-containing media for several days matured into cells with phenotypic and functional characteristics of interdigitating DC
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