- ￥8041
- PeproTech
- 210-33-50UG
- 2025年08月19日
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- 详细信息
- 文献和实验
- 技术资料
- 规格：
50ug
Murine IL-33 (50ug)
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Product Details |
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Size |
50 µg |
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Species |
Mouse |
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Published Species |
Non-human primate, Mouse, Human |
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Expression system |
E. coli |
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Amino acid sequence |
SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI |
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Molecular weight |
17.5 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<1 EU/µg |
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Activity |
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 0.5 ng/ml, corresponding to a specific activity of 2 x 10^6 units/mg. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications |
Tested Dilution |
Publications |
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Functional Assay (Functional) |
Assay-dependent |
1 Publication |
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In vitro Assay (IV) |
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41 Publications |
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Miscellaneous PubMed (Misc) |
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13 Publications |
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Product Specific Information
210-33-1MG will be provided as 10 x 100 µg (210-33-100UG).
210-33-250UG will be provided as multiple 50 µg (210-33-50UG) and 100 µg (210-33-100UG) vials. 210-33-500UG will be provided as 5 x 100 µg (210-33-100UG).
Recombinant Murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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Mouse IL-33 Protein (210-33-100UG) in Functional |
| Bioassay analysis of Mouse IL-33 Recombinant Protein, PeproTech® (Product # 210-33-1MG). |
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文献和实验[1]Leimkühler NB, Gleitz HFE, Ronghui L, Snoeren IAM, Fuchs SNR, Nagai JS, Banjanin B, Lam KH, Vogl T, Kuppe C, Stalmann USA, Büsche G, Kreipe H, Gütgemann I, Krebs P, Banz Y, Boor P, Tai EW, Brümmendorf TH, Koschmieder S, Crysandt M, Bindels E, Kramann R, Costa IG, Schneider RK. Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell Stem Cell. 2021 Apr 1;28(4):637-652.e8. doi: 10.1016/j.stem.2020.11.004. Epub 2020 Dec 9. PMID: 33301706; PMCID: PMC8024900.
[2]Panova V, Gogoi M, Rodriguez-Rodriguez N, Sivasubramaniam M, Jolin HE, Heycock MWD, Walker JA, Rana BMJ, Drynan LF, Hodskinson M, Pannell R, King G, Wing M, Easton AJ, Oedekoven CA, Kent DG, Fallon PG, Barlow JL, McKenzie ANJ. Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11. Mucosal Immunol. 2021 Jan;14(1):26-37. doi: 10.1038/s41385-020-0298-2. Epub 2020 May 26. PMID: 32457448; PMCID: PMC7790759.
[3]Drube S, Müller S, Weber F, Wegner P, Böttcher-Loschinski R, Gaestel M, Hutloff A, Kamradt T, Andreas N. IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction. Immunology. 2021 May;163(1):86-97. doi: 10.1111/imm.13305. Epub 2021 Jan 27. PMID: 33427298; PMCID: PMC8044339.
[4]Sabbaghi F, Ullner L, Bohn T, Hahlbrock J, Bopp T, Schmitt E, Klein M, Stassen M. In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9. J Immunol. 2021 Jan 1;206(1):67-76. doi: 10.4049/jimmunol.1900310. Epub 2020 Dec 2. PMID: 33268486.
[5]Jin R, Xu J, Gao Q, Mao X, Yin J, Lu K, Guo Y, Zhang M, Cheng R. IL-33-induced neutrophil extracellular traps degrade fibronectin in a murine model of bronchopulmonary dysplasia. Cell Death Discov. 2020 May 4;6:33. doi: 10.1038/s41420-020-0267-2. PMID: 32377396; PMCID: PMC7198621.
[6]Bromley SK, Akbaba H, Mani V, Mora-Buch R, Chasse AY, Sama A, Luster AD. CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response. Cell Rep. 2020 Sep 1;32(9):108085. doi: 10.1016/j.celrep.2020.108085. PMID: 32877667; PMCID: PMC7520726.
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