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- 详细信息
- 技术资料
- 规格:
100ug
Human ICAM-2 Fc (100ug)
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Product Details |
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Size |
100 μg |
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Species |
Human |
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Expression system |
CHO cells |
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Amino acid sequence |
SDEKVFEVHV RPKKLAVEPK GSLEVNCSTT CNQPEVGGLE TSLDKILLDE QAQWKHYLVS NISHDTVLQC HFTCSGKQES MNSNVSVYQP PRQVILTLQP TLVAVGKSFT IECRVPTVEP LDSLTLFLFR GNETLHYETF GKAAPAPQEA TATFNSTADR EDGHRNFSCL AVLDLMSRGG NIFHKHSAPK MLEIYEPVSD SQGGPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK |
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Tag |
Fc-tag |
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Molecular weight |
48.5 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<1 EU/µg |
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Activity |
Determined by its ability to support the adhesion of PMA-stimulated HSB2 cells to plates pre-coated with ICAM-3 Fc. The ED50 for this effect is 1.0-5.0 ug/ml. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications Tested Dilution Publications |
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Functional Assay (Functional) Assay-dependent - |
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Product Specific Information
PeproTech's CHO-derived Recombinant Human ICAM-2 Fc is a glycosylated, disulfide-linked homodimer of 435 amino- acid-residues whose monomer consists of the 202-amino-acid extracellular portion of ICAM-2 fused to the 231-amino-acid
length Fc portion of human IgG by two glycine residues. The calculated molecular weight of monomeric CHO cell-derived Recombinant Human ICAM-2 Fc is 48.5 kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 70-80 kDa by SDS-PAGE analysis under reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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