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- 详细信息
- 文献和实验
- 技术资料
- 库存:
充足
- 供应商:
GIBCO
- 英文名:
Human CTGF
- 规格:
1mg
Human CTGF (1mg)
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Product Details |
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Size |
20 µg |
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Species |
Human |
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Published Species |
Rat, Mouse, Human, Chicken |
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Expression system |
E. coli |
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Amino acid sequence |
GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA |
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Molecular weight |
11 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
95% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<1 EU/µg |
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Activity |
Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications |
Tested Dilution |
Publications |
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Western Blot (WB) |
Assay-dependent |
- |
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ELISA (ELISA) |
Assay-dependent |
- |
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Functional Assay (Functional) |
Assay-dependent |
1 Publication |
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In vitro Assay (IV) |
- |
19 Publications |
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Miscellaneous PubMed (Misc) |
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2 Publications |
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Product Specific Information
Recombinant Human CTGF is an 11.0 kDa protein consisting of 97 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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文献和实验[1]Chen X, Zhang Y, Qian W, Han L, Li W, Duan W, Wu Z, Wang Z, Ma Q. Arl4c promotes the growth and drug resistance of pancreatic cancer by regulating tumor-stromal interactions. iScience. 2021 Nov 3;24(12):103400. doi: 10.1016/j.isci.2021.103400. PMID: 34849465; PMCID: PMC8609020.
[2]Wu Z, Zhou C, Yuan Q, Zhang D, Xie J, Zou S. CTGF facilitates cell-cell communication in chondrocytes via PI3K/Akt signalling pathway. Cell Prolif. 2021 Mar;54(3):e13001. doi: 10.1111/cpr.13001. Epub 2021 Feb 1. PMID: 33522639; PMCID: PMC7941231.
[3]Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, Nguyen TK, Park PK, Egranov SD, Ambati CR, Putluri N, Hawke DH, Han L, Hung MC, Danesh FR, Yang L, Lin C. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019 Mar 1;129(3):1129-1151. doi: 10.1172/JCI121987. Epub 2019 Feb 11. PMID: 30741721; PMCID: PMC6391108.
[4]Wang Y, He G, Guo Y, Tang H, Shi Y, Bian X, Zhu M, Kang X, Zhou M, Lyu J, Yang M, Mu M, Lai F, Lu K, Chen W, Zhou B, Zhang J, Tang K. Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix. J Cell Mol Med. 2019 Aug;23(8):5475-5485. doi: 10.1111/jcmm.14430. Epub 2019 May 31. PMID: 31148334; PMCID: PMC6653097.
[5]Kanda A, Noda K, Hirose I, Ishida S. TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane. Sci Rep. 2019 Jan 24;9(1):673. doi: 10.1038/s41598-018-36917-9. PMID: 30679596; PMCID: PMC6346093.
[6]Sato-Matsubara M, Matsubara T, Daikoku A, Okina Y, Longato L, Rombouts K, Thuy LTT, Adachi J, Tomonaga T, Ikeda K, Yoshizato K, Pinzani M, Kawada N. Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling. J Biol Chem. 2017 Nov 17;292(46):18961-18972. doi: 10.1074/jbc.M117.793794. Epub 2017 Sep 15. PMID: 28916723; PMCID: PMC5706471.
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