- ￥20203
- PeproTech
- 110-08-500UG
- 2025年07月08日
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500ug
Human KLF4-TAT (500ug)
KLF4 is a member of the Kruppel-like factor (KLF) family of zinc finger transcription factors.
Members of this family share 3 contiguous C2H2-type zinc fingers at the carboxyl terminus
that comprise the DNA-binding domain. KLF4 is highly expressed in skin and gut epithelial
tissues, but is also found in various other cells and tissues, including vascular endothelial cells,
lymphocytes, lung, and testis. It is an important regulator of the cell cycle, transcription, and
cell differentiation. Together with Sox2, Oct4, and cMyc, KLF4 can induce the reprogramming
of primary human fibroblasts to a pluripotent state. KLF4 and other transcription factors can be
introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction
using TAT fusion proteins represents an alternative methodology for introducing transcription
factors into primary, as well as transformed, cells.
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Human KLF4-TAT (500ug)
￥20203
