- ￥26143
- PeproTech
- 100-13A-500UG
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 规格：
500ug
Human PDGF-AA (500ug)
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Product Details |
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Size |
50 µg |
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Species |
Human |
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Published Species |
Dog, Rat, Non-human primate, Camelid, Amphibian, Zebrafish, Human, Mouse, Lizard |
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Expression system |
E. coli |
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Amino acid sequence |
SIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT |
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Molecular weight |
28.5 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<1 EU/µg |
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Activity |
Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 1.0-3.0 ng/ml. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications |
Tested Dilution |
Publications |
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Western Blot (WB) |
Assay-dependent |
- |
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ELISA (ELISA) |
Assay-dependent |
1 Publication |
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Functional Assay (Functional) |
Assay-dependent |
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In vitro Assay (IV) |
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133 Publications |
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Miscellaneous PubMed (Misc) |
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23 Publications |
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Product Specific Information
Recombinant Human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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Human PDGF-AA Protein (100-13A-50UG) in Functional
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| Bioassay analysis of Human PDGF-AA Recombinant Protein, PeproTech® (Product # 100-13A-1MG). |
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文献和实验[1]Wienke J, Visser LL, Kholosy WM, Keller KM, Barisa M, Poon E, Munnings-Tomes S, Himsworth C, Calton E, Rodriguez A, Bernardi R, van den Ham F, van Hooff SR, Matser YAH, Tas ML, Langenberg KPS, Lijnzaad P, Borst AL, Zappa E, Bergsma FJ, Strijker JGM, Verhoeven BM, Mei S, Kramdi A, Restuadi R, Sanchez-Bernabeu A, Cornel AM, Holstege FCP, Gray JC, Tytgat GAM, Scheijde-Vermeulen MA, Wijnen MHWA, Dierselhuis MP, Straathof K, Behjati S, Wu W, Heck AJR, Koster J, Nierkens S, Janoueix-Lerosey I, de Krijger RR, Baryawno N, Chesler L, Anderson J, Caron HN, Margaritis T, van Noesel MM, Molenaar JJ. Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy. Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4. PMID: 38181797; PMCID: PMC10864003.
[2]Luo Y, Cao X, Chen J, Gu J, Yu H, Sun J, Zou J. Platelet-Derived Growth Factor-Functionalized Scaffolds for the Recruitment of Synovial Mesenchymal Stem Cells for Osteochondral Repair. Stem Cells Int. 2022 Jan 27;2022:2190447. doi: 10.1155/2022/2190447. PMID: 35126525; PMCID: PMC8813289.
[3]Yamanaka K, Nakamura K, Shibahara T, Takashima M, Takaki H, Hidaka M, Komori M, Yoshikawa Y, Wakisaka Y, Ago T, Kitazono T. Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice. Glia. 2023 Mar;71(3):541-559. doi: 10.1002/glia.24292. Epub 2022 Nov 2. PMID: 36321558.
[4]Copaciu R, Rashidian J, Lloyd J, Yahyabeik A, McClure J, Cummings K, Su Q. Characterization of an IDH1 R132H Rabbit Monoclonal Antibody, MRQ-67, and Its Applications in the Identification of Diffuse Gliomas. Antibodies (Basel). 2023 Feb 6;12(1):14. doi: 10.3390/antib12010014. PMID: 36810519; PMCID: PMC9944093.
[5]Weng M, Hu H, Graus MS, Tan DS, Gao Y, Ren S, Ho DHH, Langer J, Holzner M, Huang Y, Ling GS, Lai CSW, Francois M, Jauch R. An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming. Sci Adv. 2023 Aug 25;9(34):eadh2501. doi: 10.1126/sciadv.adh2501. Epub 2023 Aug 23. PMID: 37611093; PMCID: PMC10446497.
[6]Hamanaka G, Hernández IC, Takase H, Ishikawa H, Benboujja F, Kimura S, Fukuda N, Guo S, Lok J, Lo EH, Arai K. Myelination- and migration-associated genes are downregulated after phagocytosis in cultured oligodendrocyte precursor cells. J Neurochem. 2023 Nov;167(4):571-581. doi: 10.1111/jnc.15994. Epub 2023 Oct 24. PMID: 37874764; PMCID: PMC10842993.
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