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Anti-Mouse CD3 SAFIRE Purified

(500 μg)
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  • ¥2779
  • BioGems已认证
  • 05112-25-500
  • 2026年02月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 克隆性

      17A2

    • 标记物

      SAFIRE Purified

    • 规格

      500 μg

     

    T细胞扩增用抗体,CD3/C0D28功能性抗体

    助力CAR-T及免疫细胞治疗研究

    产品细节图片1

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    图标文献和实验
    该产品被引用文献

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    [2] Xie Y, Zhang Y, Wei X, et al. Jianpi Huayu Decoction Attenuates the Immunosuppressive Status of H22 Hepatocellular Carcinoma-Bearing Mice: By Targeting Myeloid-Derived Suppressor Cells. Front Pharmacol. 2020;11:16. Published 2020 Feb 18. doi:10.3389/fphar.2020.00016

    [3] Li C, Lin Y, Zheng H, et al. Glutamate transporter SLC1A6 promotes resistance to immunotherapy in cancer. Cancer Immunol Immunother. 2025;74(8):240. Published 2025 Jun 7. doi:10.1007/s00262-025-04074-4

    [4] Han J, Gao F, Geng S, et al. Minicircle DNA-Engineered CAR T Cells Suppressed Tumor Growth in Mice. Mol Cancer Ther. 2020;19(1):178-186. doi:10.1158/1535-7163.MCT-19-0204

    [5] Zhang Z, Yang Y, Chen Y, Su J, Du W. Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells. Mol Cell. 2024;84(17):3354-3370.e7. doi:10.1016/j.molcel.2024.07.021

    [6] Xu W, Hu M, Lu X, et al. Inhibition of PCSK9 enhances the anti-hepatocellular carcinoma effects of TCR-T cells and anti-PD-1 immunotherapy. Int J Biol Sci. 2024;20(10):3942-3955. Published 2024 Jul 15. doi:10.7150/ijbs.93668

    [7] Zhang X, Chen R, Huo Z, et al. Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer. Cancer Cell Int. 2024;24(1):225. Published 2024 Jun 29. doi:10.1186/s12935-024-03412-3

    [8] Wang R, Li C, Cheng Z, et al. H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response. Cell Rep. 2024;43(9):114686. doi:10.1016/j.celrep.2024.114686

    [9] Tang D, Zhao L, Yan F, Ren C, Xu K, Zhao K. Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice. J Immunother Cancer. 2024;12(6):e008364. Published 2024 Jun 25. doi:10.1136/jitc-2023-008364

    [10] Fan Z, Yi Z, Li S, He J. Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8+T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice. BMC Biotechnol. 2025;25(1):30. Published 2025 Apr 16. doi:10.1186/s12896-025-00963-9

    [11] Ren H, Chen Y, Zhu Z, et al. FOXO1 regulates Th17 cell-mediated hepatocellular carcinoma recurrence after hepatic ischemia-reperfusion injury. Cell Death Dis. 2023;14(6):367. Published 2023 Jun 17. doi:10.1038/s41419-023-05879-w

    [12] Fan W, Wang X, Zeng S, et al. Global lactylome reveals lactylation-dependent mechanisms underlying TH17 differentiation in experimental autoimmune uveitis. Sci Adv. 2023;9(42):eadh4655. doi:10.1126/sciadv.adh4655

    [13] Li P, Zhou D, Chen D, et al. Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer. J Biomed Sci. 2023;30(1):47. Published 2023 Jun 28. doi:10.1186/s12929-023-00930-6

    [14] Liu Y, Zhou Y, Huang KH, et al. EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC. Aging (Albany NY). 2019;11(23):11054-11072. doi:10.18632/aging.102510

    [15] Dabbah-Krancher G, Ruchinskas A, Kallarakal MA, et al. A20 intrinsically influences human effector T-cell survival and function by regulating both NF-κB and JNK signaling. Eur J Immunol. 2024;54(12):e2451245. doi:10.1002/eji.202451245

    [16] Yu W, Wang K, He Y, et al. The potential role of lung microbiota and lauroylcarnitine in T-cell activation associated with checkpoint inhibitor pneumonitis. EBioMedicine. 2024;106:105267. doi:10.1016/j.ebiom.2024.105267

    [17] Zhang XY, Shi JB, Jin SF, et al. Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape. Cancer Commun (Lond). 2024;44(6):670-694. doi:10.1002/cac2.12545

    [18] Shang S, Yang C, Chen F, et al. ID1 expressing macrophages support cancer cell stemness and limit CD8+ T cell infiltration in colorectal cancer. Nat Commun. 2023;14(1):7661. Published 2023 Nov 23. doi:10.1038/s41467-023-43548-w

    [19] Wang X, Fang Y, Liang W, et al. Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer. Cancer Cell. 2024;42(10):1729-1746.e8. doi:10.1016/j.ccell.2024.08.019

    [20] Lkhagva-Yondon E, Seo MS, Oh Y, et al. The aryl hydrocarbon receptor controls mesenchymal stromal cell-mediated immunomodulation via ubiquitination of eukaryotic elongation factor-2 kinase. Cell Death Dis. 2023;14(12):812. Published 2023 Dec 9. doi:10.1038/s41419-023-06341-7

    [21] Xu G, Wang J, Qu Y, et al. GSTP1 improves CAR-T cell proliferation and cytotoxicity to combat lymphoma. Front Immunol. 2025;16:1665407. Published 2025 Sep 26. doi:10.3389/fimmu.2025.1665407

    [22] Wang F, Li Y, Yang Z, et al. Targeting IL-17A enhances imatinib efficacy in Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia. Nat Commun. 2024;15(1):203. Published 2024 Jan 3. doi:10.1038/s41467-023-44270-3

    [23] Li S, Feng J, Wu F, et al. TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T-cell numbers. EMBO Rep. 2020;21(10):e49425. doi:10.15252/embr.201949425

    [24] Nahmad AD, Reuveni E, Goldschmidt E, et al. Frequent aneuploidy in primary human T cells after CRISPR-Cas9 cleavage. Nat Biotechnol. 2022;40(12):1807-1813. doi:10.1038/s41587-022-01377-0

    [25] Chen X, Huang D, Zhao L, et al. Fluvastatin Promotes Treg Cell Production in Allogeneic Immune Reaction and Suppresses Inflammatory Response. Immun Inflamm Dis. 2025;13(2):e70165. doi:10.1002/iid3.70165

    [26] Han K, Li SS, Pan W, et al. ERK/MEK Pathway Regulates Th17 Cell Differentiation in Patients with Pemphigus Vulgaris. Indian J Dermatol. 2023;68(6):724. doi:10.4103/ijd.ijd_924_22

    [27] Zhan Y, Cao J, Ji L, et al. Impaired mitochondria of Tregs decreases OXPHOS-derived ATP in primary immune thrombocytopenia with positive plasma pathogens detected by metagenomic sequencing. Exp Hematol Oncol. 2022;11(1):48. Published 2022 Sep 1. doi:10.1186/s40164-022-00304-y

    [28] Kim M, Kim SD, Kim KI, et al. Dynamics of T Lymphocyte between the Periphery and the Brain from the Acute to the Chronic Phase Following Ischemic Stroke in Mice. Exp Neurobiol. 2021;30(2):155-169. doi:10.5607/en20062

    [29] Han SM, Park ES, Park J, et al. Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice. Nat Commun. 2023;14(1):8512. Published 2023 Dec 21. doi:10.1038/s41467-023-44181-3

    [30] Chen Z, Hu Y, Gong Y, et al. Interleukin-33 alleviates psoriatic inflammation by suppressing the T helper type 17 immune response. Immunology. 2020;160(4):382-392. doi:10.1111/imm.13203

    [31] Mai Q, Du Q, Zeng F, et al. Galectin-3 suppresses CD8+ T cells function via myeloid-derived suppressor cells recruitment in cervical cancer. Int J Biol Macromol. 2025;311(Pt 4):143683. doi:10.1016/j.ijbiomac.2025.143683

    [32] Zhang Z, Ji W, Huang J, et al. Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients. Clin Transl Med. 2022;12(11):e1072. doi:10.1002/ctm2.1072

    [33] Jang SE, Jeong JJ, Choi SY, Kim H, Han MJ, Kim DH. Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 Attenuate Gardnerella vaginalis-Infected Bacterial Vaginosis in Mice. Nutrients. 2017;9(6):531. Published 2017 May 23. doi:10.3390/nu9060531

    [34] Huang H, Guo F, Deng X, et al. Modulation of T Cell Responses by Fucoidan to Inhibit Osteogenesis. Front Immunol. 2022;13:911390. Published 2022 Jun 23. doi:10.3389/fimmu.2022.911390

    [35] Lee MH, Lee YS, Kim HJ, Han CH, Kang SU, Kim CH. Non-thermal plasma inhibits mast cell activation and ameliorates allergic skin inflammatory diseases in NC/Nga mice. Sci Rep. 2019;9(1):13510. Published 2019 Sep 18. doi:10.1038/s41598-019-49938-9

    [36] Wang Y, Xiang Q, Wu Y, et al. Mesenchymal Stem Cell-Derived Exosomes Inhibit Stim1-Orai1 Signaling and Calcium Overload-Induced Mitochondrial Damage of Follicular Helper T Cells in Lupus. Biomater Res. 2025;29:0255. Published 2025 Sep 22. doi:10.34133/bmr.0255

    [37] Kaisar-Iluz N, Arpinati L, Shaul ME, et al. The Bilateral Interplay between Cancer Immunotherapies and Neutrophils' Phenotypes and Sub-Populations. Cells. 2022;11(5):783. Published 2022 Feb 23. doi:10.3390/cells11050783

    [38] Yu A, Hu J, Fu L, et al. Bladder cancer intrinsic LRFN2 drives anticancer immunotherapy resistance by attenuating CD8+ T cell infiltration and functional transition. J Immunother Cancer. 2023;11(10):e007230. doi:10.1136/jitc-2023-007230

    [39] Qian Y, Sun Y, Shi P, et al. Development of LAG-3/FGL1 blocking peptide and combination with radiotherapy for cancer immunotherapy. Acta Pharm Sin B. 2024;14(3):1150-1165. doi:10.1016/j.apsb.2023.12.011

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    [44] Feng S, Wang D, Jin Y, et al. Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity. Cell Rep. 2024;43(6):114300. doi:10.1016/j.celrep.2024.114300

     

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