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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
储存于-20 ° C
- 保质期：
1年
- 英文名：
3-Cyano-7-ethoxycoumarin
- 库存：
100
- 供应商：
艾美捷科技
- CAS号：
无
- 规格：
10mM (in 1mL DMSO)
3-Cyano-7-ethoxycoumarin，3-Cyano-7-ethoxycoumarin，3-Cyano-7-ethoxycoumarin,3-Cyano-7-ethoxycoumarin
3-Cyano-7-ethoxycoumarin-3-Cyano-7-ethoxycoumarin
产品货号：APE-B7714-51
产品规格：10mM (in 1mL DMSO)
荧光P450底物
Metabolism|CYP3A/CYP450
3-Cyano-7-ethoxycoumarin-3-Cyano-7-ethoxycoumarin储存于-20 ° C
点击：3-Cyano-7-ethoxycoumarin-3-Cyano-7-ethoxycoumarin查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多APExBIO公司特色小分子抑制剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Use of 7-Ethoxycoumarin to Monitor Multiple Enzymes in the Human CYP1, CYP2, and CYP3 Families
7-Ethoxycoumarin is metabolized by many cytochrome P450 enzymes active in foreign compound metabolism and has been used as a prototypic substrate to monitor P450 (P450) activity in both hepatic and extrahepatic tissues. A spectrofluorometric
Use of 7-Ethoxycoumarinto Monitor Multiple Enzymesin the Human CYP1, CYP2, and CYP3 Families
of a general P4.50 substrate is 7-ethoxycoumarin. Enzyme kinetic analysis with human liver microsomes indicates that 7-ethoxycoumarin is metabolized by at least two P450 enzymes or by two groups of P450 enzymes that are kinetically distmguishable
have been ldentlfied for cDNA-expressed CYP2B6, including I-l-ethoxycoumarin (3 , 7 , 8 ), benzo[a]pyrene (9 ), phenanthrene (10 ), and methoxychlor (11 ). However, little is known regardmg the role of this P450 in drug metabolism, although cDNA-expressed CYP
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