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文献和实验Assessing Fc Glycan Heterogeneity of Therapeutic Recombinant Monoclonal Antibodies Using NP-HPLC
Recombinant monoclonal antibodies (rMAbs) are becoming major human therapeutics to treat life-threatening diseases such as cancer. These rMAbs are produced using either in vitro cell culture processes or transgenic technology in animals
,Bohm G, lilie H, et al. Folding proteins. In:Creighton T E ed. Protein Function: A Practical Approach, 2nd.New York: IRL,1997,57-99 [7]CowleyDT, MackinRB. Expression, purification and charaterization of recombinant human proinsulin. FEBS Lett,1997
Protein M r aa seq S 20,w S max /S R s (nm) Source
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