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- 2025年07月11日
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文献和实验23 Endonuclease G Isolation and Assays
of a 29-kDa polypeptide, accounts for nearly all of the potent DNA endonuclease activity identified in crude protein extracts of isolated mitochondria (3 ). The 1133-bp (base pairs) cDNA for the human Endonuclease G gene has been mapped to chromosome 9q34.1 (4 ).
APP-Based Transgenic Models: The APP23 Model
transgenic mouse. This paper describes the development and assessment of this human amyloid precursor protein overexpression model. We summarize histopathological and biochemical, cognitive and behavioral observations made in heterozygous APP23 mice
Detection of t(2;5)(p23;q35)Translocation by Long-Range PCR of Genomic DNA
with a protein kinase gene (anaplastic lymphoma kinase [ALK ]) on chromosome 2p23. This results in the formation of a fusion protein with the N-terminal sequence derived from the NPM gene and the C-terminal cytoplasmic sequences from the ALK gene, including
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