1 Mollugin prevents CLP-induced sepsis in mice by inhibiting TAK1-NF-κB/MAPKs pathways and activating Keap1-Nrf2 pathway in macrophages / Mouse serum
2 Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288. Mouse serum
3 A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages Int Immunopharmacol.2023 Nov;124(Pt B):110965. Mouse serum
4 Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy Stem Cell Res Ther.2023 Sep 7;14(1):237. Mouse serum
5 Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway Mol Neurobiol.2023 Sep 2. Mouse cell culture supernatants
6 A High-Fat, High-Cholesterol Diet Promotes Intestinal Inflammation by Exacerbating Gut Microbiome Dysbiosis and Bile Acid Disorders in Cholecystectomy Nutrients.2023 Sep 1;15(17):3829. Mouse Tissues
7 HIF-1α inhibition in macrophages preserves acute liver failure by reducing IL-1β production FASEB J.2023 Sep;37(9):e23140. Mouse Plasma
8 A Q-marker screening strategy based on ADME studies and systems biology for Chinese herbal medicine, taking Qianghuo Shengshi decoction in treating rheumatoid arthritis as an example Mol Omics.2023 Dec 4;19(10):769-786. Mouse cell culture supernatants
9 Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase Phytother Res.2023 Oct;37(10):4587-4606. Mouse serum
10 A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases Eur J Pharmacol.2023 Sep 5:954:175840. Mouse serum
11 Parthenolide targets NLRP3 to treat inflammasome-related diseases Int Immunopharmacol.2023 Jun:119:110229. Mouse serum, cell culture supernatants
12 Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice J Sci Food Agric.2023 Aug 30;103(11):5529-5538. Mouse serum
13 Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease Int J Mol Sci.2023 Mar 14;24(6):5549. Mouse serum
14 Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair Reprod Sci.2023 Jun;30(6):1979-1993. Mouse plasma
15 Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages Int Immunopharmacol.2022 Dec;113(Pt A):109404. Mouse serum
16 Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models Acta Biomater.2022 Dec:154:424-442. Mouse cell culture supernatants
17 Combined delivery of small molecule and protein drugs as synergistic therapeutics for treating corneal neovascularization by a one-pot coassembly strategy Mater Today Bio.2022 Oct 8:17:100456. Mouse Cell culture supernatants
18 Taurine Alleviates Trimethy lamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice J Agric Food Chem. 2022 May 11;70(18):5738-5747 Mouse serum
19 Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation Acta Pharm Sin B. 2022 Feb;12(2):907-923 Mouse plasma
20 Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model Front Immunol. 2022 Apr 13;13:878832 Mouse cell culture supernatants
21 FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101 Mouse serum
22 Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein Int Immunopharmacol. 2022 Oct;111:109148 Mouse serum
23 Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation J. Med. Chem. 2022, 65, 1, 103–119 Mouse serum
24 Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer EMBO Mol Med. 2022 Jan 11;14(1):e14502 Mouse cell culture supernatants
25 Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β Front Pharmacol. 2022 Jun 14;13:911157 Mouse serum
26 Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethy lamine N-oxide (TMAO) pathway in mice Phytomedicine. 2022 Jul;101:154104 Mouse plasma
27 Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice Front Endocrinol (Lausanne). 2022 May 30;13:887238 Mouse serum
28 Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury Front Cell Neurosci. 2022 May 20;16:915969 Mouse Tissue Lysates
29 4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway J Cell Mol Med. 2022 Mar;26(5):1515-1529 Mouse cell culture supernatants
30 The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251 Mouse Tissue Homogenates
31 Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study Phytomedicine. 2021 May;85:153390 Mouse Tissue Homogenates
32 SARS - CoV -2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target Cell Res. 2021 Aug;31(8):847-860 Mouse serum,cell culture supernatants
33 Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution Adv Sci (Weinh). 2021 Feb 8;8(8):2003941 Mouse cell culture supernatants
34 Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction J Ethnopharmacol. 2021 Nov 15;280:114474 Mouse serum
35 A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS -CoV - 2 challenge Cell Rep. 2021 Dec 14;37(11):110112 Mouse cell culture supernatants
36 A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement Acta Biomater. 2021 May;126:524-536 Mouse cell culture supernatants
37 Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes J Neuroinflammation. 2020 Feb 5;17(1):50 Mouse cell culture medium
38 Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation Front Pharmacol. 2020 Oct 2;11:577319 Mouse cell culture supernatants
39 Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023 Mouse cell culture supernatants
40 Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1 Pathog Dis. 2020 Mar 1;78(2):ftaa016 Mouse serum
41 Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury J Neurotrauma. 2019 Mar 19;36(6):903-918 Mouse cell culture supernatants
42 MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway Int J Mol Med. 2019 Feb;43(2):779-790 Mouse cell culture supernatants
43 ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death Front Immunol. 2018 Nov 14;9:2647 Mouse cell culture supernatants,Tissue
44 Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways J Dermatol Sci. 2018 Feb;89(2):127-135 Mouse serum
45 miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice Transplant Proc. 2018 Dec;50(10):3831-3839 Mouse serum, cell culture supernatants
46 PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury Mediators Inflamm. 2018 Oct 3;2018:6757368 Mouse BALF
47 microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958 Mouse cell culture supernatants
48 Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages Carbon.Volume 113, March 2017, Pages 176-191 Mouse cell culture supernatants
49 Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure Am J Transl Res. 2017 Nov 15;9(11):4925-4935 Mouse serum
50 MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4 Transplant Proc. 2016 Oct;48(8):2809-2814 Mouse serum, cell culture supernatants
51 CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment Sci Rep. 2015 Nov 3;5:15948 Mouse Serum
52 miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6 PLoS One. 2014 Jul 2;9(7):e101530 Mouse cell culture supernatants
53 Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells J Ethnopharmacol. 2013 Jun 21;148(1):271-6