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- 湖北武汉
- E-AB-70034
- 2025年10月22日
- WB
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12个月
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 抗体英文名：
EGFR Polyclonal Antibody
- 抗体名：
EGFR Polyclonal Antibody_货号:E-AB-70034_多克隆抗体
- 规格：
200μL/120μL/60μL
| 规格： | 200μL | 产品价格： | ￥3300.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥2220.0 |
| 规格： | 60μL | 产品价格： | ￥1380.0 |
EGFR Polyclonal Antibody
| Verified Samples |
Verified Samples in WB: A549, HepG2, MCF-7, HCT116
|
| Dilution |
WB 1:500-1:2000
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse EGFR
|
| Abbre |
EGFR
|
| Synonyms |
Avian erythroblastic leukemia viral (v erb b) oncogene homolog, Cell growth inhibiting protein 40, Cell proliferation inducing protein 61, EGF R, EGFR, Epide, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog)
|
| Swissprot |
P00533, Q01279
|
| Calculated MW |
134 kDa
|
| Observed MW |
175 kDa
|
| Cellular Localization |
Secreted and Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. Nucleus membrane. Endosome. Endosome membrane. Nucleus. In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER. Endocytosed upon activation by ligand. Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF).
|
| Concentration |
110 μg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH 7.4.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer, Signal Transduction
|
| Conjugation |
Unconjugated
|
| Background |
EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
|
EGFR Polyclonal AntibodyElabscience®提供8000+经过实验验证的高品质一抗，主要包括： 流式抗体、 单抗、 多抗、 重组抗体、 内参/标签抗体、 乙酰化/磷酸化/甲基化抗体、 磁珠/凝胶偶连抗体、 病毒抗体等。
EGFR Polyclonal AntibodyStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
EGFR Polyclonal Antibody产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
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