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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
YAP1 Polyclonal Antibody_货号:E-AB-62344_多克隆抗体
- 抗体英文名:
YAP1 Polyclonal Antibody
- 应用范围:
IHC;IF
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 目录编号:
E-AB-62344
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL
| 规格: | 200μL | 产品价格: | ¥3580.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥2220.0 |
| 规格: | 60μL | 产品价格: | ¥1380.0 |
货号:E-AB-62344
| Verified Samples |
Verified Samples in IHC:Human liver cancer,Human placenta,Rat brain
Verified Samples in IF: C6, NIH/3T3 |
| Dilution |
IHC 1:50-1:100, IF 1:50-1:200
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant fusion protein of human YAP1 (NP_001123617.1).
|
| Abbre |
YAP1
|
| Synonyms |
COB1;YAP;YAP2;YAP65;YKI;YAP1抗体
|
| Swissprot |
P46937
|
| Cellular Localization |
Cytoplasm. Nucleus. Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.
|
| Concentration |
1mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
|
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