手机验证
COL17A1 Polyclonal Antibody_货号:E-AB-19718_多克隆抗体
COL17A1 Polyclonal Antibody
IHC;ELISA
Rabbit
Human; Mouse
12个月
E-AB-19718
科研级别
999
武汉伊莱瑞特生物科技股份有限公司
Unconjugated
Polyclonal
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
液体
IgG
200μL/120μL/60μL/20μL
规格: | 200μL | 产品价格: | ¥2365.0 |
---|---|---|---|
规格: | 120μL | 产品价格: | ¥1640.0 |
规格: | 60μL | 产品价格: | ¥1010.0 |
规格: | 20μL | 产品价格: | ¥420.0 |
Verified Samples |
Verified Samples in IHC:Human colorectal cancer,Human liver cancer
|
Dilution |
IHC 1:50-1:200, ELISA 1:5000-1:10000
|
Clonality |
Polyclonal
|
Isotype |
IgG
|
Immunogen |
Synthetic peptide of human COL17A1
|
Abbre |
COL17A1
|
Synonyms |
180 kDa bullous pemphigoid antigen 2;Alpha 1 type XVII collagen;BA16H23.2;BP 180;BP180;BPA 2;BPAG 2;BPAG2;Bullous pemphigoid antigen 2;COL17A1;Collagen 17;Collagen alpha 1 XVII chain;Collagen alpha 1(XVII) chain;Collagen alpha1 XVII chain;Collagen type XVII alpha 1;Collagen XVII alpha 1 polypeptide;CollagenXVII;Epidermolysis bullosa junctional localisata variant;FLJ60881;KIAA0204;LAD 1;LAD1抗体
|
Swissprot |
Q9UMD9
|
Cellular Localization |
Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome.120 kDa linear IgA disease antigen and 97 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane.
|
Concentration |
1.38 mg/mL
|
Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
|
Purification Method |
Antigen affinity purification
|
Research Areas |
Cancer; Signal Transduction
|
Conjugation |
Unconjugated
|
Background |
COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
|
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
自2012年第一篇引用文献问世,至2023年8月,Elabscience已协助各地科研工作者发表超13,000篇SCI文献,包括行业顶/级期刊Nature Medicine, Nature, Cell, Signal Transduction and Targeted Therapy, Circulation, Molecular Cancer, Immunity, Advanced Materials等,总影响因子(IF)59472.59,其中IF≥30的文献超30篇,最高影响因子为66.849,发文单位包含北京大学、中国科学技术大学、浙江大学、斯坦福大学、耶鲁大学、柏林夏里特大学等国内外各大高校。
每年引用文献数量持续增长,保持逐年30%+高增长率,可以预见,Elabscience产品将帮助更多科研工作者发表高质量SCI论文。
文献详情查看>>>>