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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
KDM3B Polyclonal Antibody_货号:E-AB-18178_多克隆抗体
- 抗体英文名:
KDM3B Polyclonal Antibody
- 应用范围:
IHC;ELISA
- 宿主:
Rabbit
- 适应物种:
Human; Mouse
- 保质期:
12个月
- 目录编号:
E-AB-18178
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL/20μL
| 规格: | 200μL | 产品价格: | ¥2365.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥1640.0 |
| 规格: | 60μL | 产品价格: | ¥1010.0 |
| 规格: | 20μL | 产品价格: | ¥420.0 |
货号:E-AB-18178
| Verified Samples |
Verified Samples in IHC:Human thyroid cancer
|
| Dilution |
IHC 1:30-1:150, ELISA 1:5000-1:10000
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Synthetic peptide of human KDM3B
|
| Abbre |
KDM3B
|
| Synonyms |
5qNCA;C5orf7;JHDM2B;JmjC domain containing histone demethylation protein 2B;JmjC domain-containing histone demethylation protein 2B;jmjd1b;Jumonji domain containing 1B;Jumonji domain containing protein 1B;Jumonji domain-containing protein 1B;KDM3B;KDM3B;KIAA1082;Lysine (K) specific demethylase 3B;Lysine-specific demethylase 3B;NET22;Nuclear protein 5qNCA抗体
|
| Swissprot |
Q7LBC6
|
| Cellular Localization |
Nucleus.
|
| Concentration |
1.26 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
|
| Purification Method |
Antigen affinity purification
|
| Research Areas |
Cancer; Epigenetics and Nuclear Signaling
|
| Conjugation |
Unconjugated
|
| Background |
JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
|
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