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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
182182-32-7
- 规格:
10 mM * 1 mL/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1760.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥1600.0 |
| 规格: | 50 mg | 产品价格: | ¥2560.0 |
| 规格: | 100 mg | 产品价格: | ¥4000.0 |
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Exatecan Intermediate 7
CAS No. : 182182-32-7
MCE 国际站:Exatecan Intermediate 7
产品活性:Exatecan Intermediate 7 是 Exatecan (HY-13631) 的中间体。Exatecan (DX-8951) 是一种 DNA 拓扑异构酶 I (topoisomerase I) 抑制剂,IC50 值为 2.2 μM (0.975 μg/mL),可用于癌症研究。Exatecan Intermediate 7 可用于合成抗体-药物偶联物 (Antibody-Drug Conjugates (ADCs))。
研究领域:Cell Cycle/DNA Damage
作用靶点:Topoisomerase
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文献和实验, 2005; Wilhelmsson et al., Proc Natl Acad Sci U S A 103:17513-17518, 2006; Sofroniew, Trends Neurosci 32:638-647, 2009; Sofroniew and Vinters, Acta Neuropathol 119:7-35, 2010). The understanding of astrocyte activation and reactive gliosis
to a primer bearing a 5′ phosphate and 3′ amino group. Reverse transcription is primed using a complementary primer, and mRNA-specific decay intermediates are identified by polymerase chain reaction amplification using a 5′-[32 P
Studying the Treatment of Chronic Hepatitis B Viral Infection in Special Populations
, the prevalence of HBV varies from a highly endemic disease (>8%) in China, Southeast Asia, and Africa to a disease of low endemicity (>2%) in North America, western Europe, and Australia. Areas with intermediate levels of prevalence (2–7%) are also noted
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