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- 2025年12月05日
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- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1256776-89-2
- 规格：
10 mM * 1 mL///1 mg
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FSHR agonist 1
CAS No. : 1256776-89-2
MCE 国际站：FSHR agonist 1
产品活性：FSHR agonist 1 是一种高亲和力和变构卵泡刺激素 (FSH) 受体 (FSHR) 激动剂，pEC50 为 7.72。FSHR agonist 1 与 TMD 形成广泛的相互作用以直接激活 FSHR。
研究领域：Vitamin D Related/Nuclear Receptor
作用靶点：Estrogen Receptor/ERR
In Vitro: The binding of FSHR agonist 1 (compound 21f) to the FSHR TMD pocket induces inward movements of TM6 and TM7, which directly results in FSHR activation.
FSHR agonist 1 (compound 21f) can activate FSHR, LHCGR and TSHR with highly potency and efficacy, while the activation potency for FSHR is more than 10-fold higher than LHCGR (pEC50 of 6.26) and TSHR (pEC50 of 6.48).
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