SJ6986,2765625-93-0

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SJ6986

CAS No. : 2765625-93-0

MCE 国际站：SJ6986

产品活性：SJ6986 是有效的、选择性的、口服有效的 GSPT1/2 降解剂，其对GSPT1 的DC₅₀ 值为2.1 nM (D_max 99%)。

研究领域：Others

作用靶点：Others

In Vitro: SJ6986 exhibits EC₅₀ values of 1.5 nM, 0.4 nM, 726 nM, 336 nM and 3583 nM in MV4-11, MHH-CALL-4, MB002, MB004 and HD-MB03 cell lines, respectively.

In Vivo: SJ6986 exhibits t_1/2 of 3.44 h by iv injection of 3 mg/kg and t_max of 0.25 h by oral administration (%F = 84) of 10 mg/kg in CD1 mice.

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