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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
986
- 靶点:
CD20
- 级别:
CD20 Antibody
- 目录编号:
CD20 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD20 Antibody
- 抗体英文名:
Purified anti-human CD20 Antibody
- 抗体名:
CD20 Antibody
- 标记物:
CD20 Antibody
- 宿主:
小鼠
- 适应物种:
人、猴
- 免疫原:
CD20 Antibody
- 亚型:
CD20 Antibody
- 形态:
CD20 Antibody
- 应用范围:
FC, CyTOF®, IHC-F, IP
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
25 ug/100 ug
| 规格: | 25 ug | 产品价格: | ¥700.0 |
|---|---|---|---|
| 规格: | 100 ug | 产品价格: | ¥1300.0 |
Purified anti-human CD20 Antibody详细如下:
Description :CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some folliculardendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated onactivated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought toform Ca conductive ion channels in the plasma membrane of B cells. The CD20 molecule isinvolved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). Itexists in a complex with MHC class I and II, CD53, CD81, and CD82.
Verified Reactivity :Human, Cynomolgus, Rhesus
Reported Reactivity :Baboon, Capuchin Monkey, Chimpanzee, Pigtailed Macaque, Squirrel Monkey
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Human tonsillar B cells
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、CyTOF®, IHC-F - Verified、IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. For immunohistochemical staining on frozen tissue sections, the suggested useof this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimalperformance for each application.
Description :CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some folliculardendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated onactivated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought toform Ca conductive ion channels in the plasma membrane of B cells. The CD20 molecule isinvolved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). Itexists in a complex with MHC class I and II, CD53, CD81, and CD82.
Verified Reactivity :Human, Cynomolgus, Rhesus
Reported Reactivity :Baboon, Capuchin Monkey, Chimpanzee, Pigtailed Macaque, Squirrel Monkey
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Human tonsillar B cells
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :FC - Quality tested、CyTOF®, IHC-F - Verified、IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. For immunohistochemical staining on frozen tissue sections, the suggested useof this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimalperformance for each application.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
3. McMichael A, et al. Eds. 1987. Leucocyte Typing III Oxford University Press. New York.
4. Polyak MJ, et al. 2002. Blood 99:3256. (IP)
5. Mack CL, et al. 2004. Pediatr. Res. 56:79. (IHC)
Product Citations:
1. Tornack J, et al. 2017. PLoS One. 12:e0169119. PubMed
2. Taft J, et al. 2021. Cell. 184(17):4447-4463.e20. PubMed
3. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
4. Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
5. Ercolano G, et al. 2021. Nat Commun. 12:2538. PubMed
6. Gruber CN, et al. 2020. Immunity. 53(3):672-684. PubMed
7. Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
8. Gunawan M, et al. 2017. Sci Rep. . 10.1038/s41598-017-16999-7. PubMed
9. Kong R, et al. 2019. Cell. 178:567. PubMed
10. Bruno TC, et al. 2017. Cancer Immunol Res. 0.831944444. PubMed
11. Cottineau J, et al. 2017. J Clin Invest. 127:1991. PubMed
12. Olin A, et al. 2018. Cell. 174:1277. PubMed
1. Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
3. McMichael A, et al. Eds. 1987. Leucocyte Typing III Oxford University Press. New York.
4. Polyak MJ, et al. 2002. Blood 99:3256. (IP)
5. Mack CL, et al. 2004. Pediatr. Res. 56:79. (IHC)
Product Citations:
1. Tornack J, et al. 2017. PLoS One. 12:e0169119. PubMed
2. Taft J, et al. 2021. Cell. 184(17):4447-4463.e20. PubMed
3. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
4. Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
5. Ercolano G, et al. 2021. Nat Commun. 12:2538. PubMed
6. Gruber CN, et al. 2020. Immunity. 53(3):672-684. PubMed
7. Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
8. Gunawan M, et al. 2017. Sci Rep. . 10.1038/s41598-017-16999-7. PubMed
9. Kong R, et al. 2019. Cell. 178:567. PubMed
10. Bruno TC, et al. 2017. Cancer Immunol Res. 0.831944444. PubMed
11. Cottineau J, et al. 2017. J Clin Invest. 127:1991. PubMed
12. Olin A, et al. 2018. Cell. 174:1277. PubMed
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Purified 抗人 CD20 抗体
¥700 - 1300










