EndoG 抗体 [7F2D7] -EndoG Antibo

EndoG 抗体 [7F2D7] ，EndoG Antibody [7F2D7] ，EndoG 抗体 [7F2D7] ,EndoG Antibody [7F2D7]

产品名称：EndoG 抗体 [7F2D7] -EndoG Antibody [7F2D7]

产品货号：PSI-PM-4581-0.02mg

产品规格：0.02mg

背景资料：EndoG Monoclonal Antibody: The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndoG also cleaves DNA in vitro.

保存建议：EndoG 抗体 [7F2D7] -EndoG Antibody [7F2D7] stored at -20℃, stable for one year

应用类型：E, WB

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