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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Mouse IL-3-dependent bone marrow mast cells
- 保存条件:
Store vial at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
大鼠
- 应用范围:
ICC, Flow, IP
- 抗体英文名:
CD117 Antibody [3C1] (FITC)
- 抗体名:
CD117 Antibody [3C1] (FITC)
- 规格:
0.5mg
CD117 抗体 [3C1] (FITC),CD117 Antibody [3C1] (FITC),CD117 抗体 [3C1] (FITC),CD117 Antibody [3C1] (FITC)
产品名称:CD117 抗体 [3C1] (FITC)-CD117 Antibody [3C1] (FITC)
产品货号:PSI-99-024-0.5mg
产品规格:0.5mg
背景资料:The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.
保存建议:CD117 抗体 [3C1] (FITC)-CD117 Antibody [3C1] (FITC)Store vial at 2-8℃
应用类型:ICC, Flow, IP
点击:CD117 抗体 [3C1] (FITC)-CD117 Antibody [3C1] (FITC)查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验中。5. 用无菌 PBS 将上述锥形试管填满(至 50 mL)。介绍样品制备。6. 洗涤。在室温、低速制动条件下,以 300 X g 离心分离试管 10 分钟。7. 裂解红细胞(BD 产品目录号:555899,10 x 溶液。在蒸馏水中使用 1 x 溶液。室温孵育 15 分钟。)8. 将 1x106 PBMC 重悬于 20 μL 染色缓冲液中(PBS 含有 5% 正常人血清)。9. 加入抗体:CD117-BV421 (c-kit)、CD7-BV510、CD57- BV605、CD8-BV650
的一些临床诊断抗体 苏州杰恩 ,上海桂康 ,上海荣圣。 7. 实验需要XXX抗体,最好是XXX公司的? 例如需要TLR4抗体,最好是Abcam的 ,那就直接咨询abcam或者其代理商试试。 8. 常用抗体品牌 abcam ,sigma ,cst ,BD,abnova ,eBioscince ,Biolegend , Proteintech,Abgent ,Prosci ,SB ,Signalway Antibody
Biotinylation of Antibody ( Contributed by Nanci Donacki ) Antibody labeling (House Ear Institute) Labeling protocols using affinity markers. Coupling Colloidal Gold to Protein (Walter Steffen
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