IKK-γ (phospho Ser85) 抗体-IKK-γ

IKK-γ (phospho Ser85) 抗体，IKK-γ (phospho Ser85) Antibody，IKK-γ (phospho Ser85) 抗体,IKK-γ (phospho Ser85) Antibody

产品名称：IKK-γ (phospho Ser85) 抗体-IKK-γ (phospho Ser85) Antibody

产品货号：PSI-79-979-0.1mg

产品规格：0.1mg

背景资料：Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.

保存建议：IKK-γ (phospho Ser85) 抗体-IKK-γ (phospho Ser85) AntibodyStore antibody at -20℃ for up to one year

应用类型：WB

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