IPO11 抗体-IPO11 Antibody

IPO11 抗体，IPO11 Antibody，IPO11 抗体,IPO11 Antibody

产品名称：IPO11 抗体-IPO11 Antibody

产品货号：PSI-63-637-400ul

产品规格：400ul

背景资料：IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).

保存建议：IPO11 抗体-IPO11 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB, IHC-P, Flow

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