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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
This Urokinase (PLAU) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human Urokinase (PLAU).
- 保存条件:
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB, IHC-P, Flow
- 抗体英文名:
Urokinase Antibody
- 抗体名:
Urokinase Antibody
- 规格:
400ul
Urokinase 抗体,Urokinase Antibody,Urokinase 抗体,Urokinase Antibody
产品名称:Urokinase 抗体-Urokinase Antibody
产品货号:PSI-63-439-400ul
产品规格:400ul
背景资料:PLAU, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders. PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin. The protein is found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A. Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain. The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis. Structurally, PLAU contains 1 EGF-like domain and 1 kringle domain.
保存建议:Urokinase 抗体-Urokinase AntibodyStore at 4℃ for three months and -20℃, stable for up to one year
应用类型:WB, IHC-P, Flow
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文献和实验Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
sequence of PrAg with other protease substrate sequences. PrAg-U2 is such a PrAg variant, one that is selectively activated by urokinase plasminogen activator (uPA). The uPA-dependent proteolytic activation of PrAg-U2 on the cell surface is readily detected
RFLP Molecular Analysis of the Urokinase-Type Plasminogen Activator Gene
attachments. One such enzyme, the serine protease urokinase-type plasminogen activator (uPA), converts enzymatically inactive plasminogen into the widely acting protease plasmin, which degrades several extracellular matrix components and also activates
Targeting proteases and their activators would retard the invasive ability of cancer cells, and has been shown to induce apoptosis in certain instances. Various methods have been developed to specifically target protease molecules
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