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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
This c ABL (ABL1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 851-881 amino acids from the C-terminal region of human c ABL (ABL1).
- 保存条件:
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB, IHC-P
- 抗体英文名:
c ABL Antibody
- 抗体名:
c ABL Antibody
- 规格:
400ul
c ABL 抗体,c ABL Antibody,c ABL 抗体,c ABL Antibody
产品名称:c ABL 抗体-c ABL Antibody
产品货号:PSI-63-152-400ul
产品规格:400ul
背景资料:The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tailfusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
保存建议:c ABL 抗体-c ABL AntibodyStore at 4℃ for three months and -20℃, stable for up to one year
应用类型:WB, IHC-P
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文献和实验A Nested RT-PCR Assay to Detect BCR/abl
) (1 ). In this chromosomal translocation, exons from a major breakpoint cluster region (M-bcr), located on chromosome 22q11, are joined to the c-abl protooncogene, located on chromosome 9q34. When this chromosomal translocation occurs in a hematopoietic stem cell
A Nested Reverse Transcription-Polymerase Chain Reaction Assay to Detect BCR/abl
) (1) . In this chromosomal translocation, exons from a major breakpoint cluster region (M-bcr), located on chromosome 22q11, are joined to the c-abl proto-oncogene, located on chromosome 9q34. When this chromosomal translocation occurs in a hematopoietic stem cell
Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein-Mediated Genome Architecture
involves conventional 3C methodology: The chromatin is cross-linked, digested with restriction enzymes, and ligated under conditions that favor intramolecular ligation. Immediately after ligation, the chromatin is immunoprecipitated using an antibody
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