SMAD2 抗体 -SMAD2 Antibody

SMAD2 抗体 ，SMAD2 Antibody ，SMAD2 抗体 ,SMAD2 Antibody

产品名称：SMAD2 抗体 -SMAD2 Antibody

产品货号：PSI-62-856-400ul

产品规格：400ul

背景资料：The protein belongs to the SMAD, a family of proteins similar to the proteins of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin.

保存建议：SMAD2 抗体 -SMAD2 Antibody Store at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB, IF

点击：SMAD2 抗体 -SMAD2 Antibody 查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。