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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
This Cyclin D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from human Cyclin D1.
- 保存条件:
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB, IHC-P, IF
- 抗体英文名:
Cyclin D1 Antibody
- 抗体名:
Cyclin D1 Antibody
- 规格:
400ul
Cyclin D1 抗体 ,Cyclin D1 Antibody ,Cyclin D1 抗体 ,Cyclin D1 Antibody
产品名称:Cyclin D1 抗体 -Cyclin D1 Antibody
产品货号:PSI-61-430-400ul
产品规格:400ul
背景资料:CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. It has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
保存建议:Cyclin D1 抗体 -Cyclin D1 Antibody Store at 4℃ for three months and -20℃, stable for up to one year
应用类型:WB, IHC-P, IF
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